Alex Loukas Selected Research

Persistent Infection

1/2022	Knockout of liver fluke granulin, Ov-grn-1, impedes malignant transformation during chronic infection with Opisthorchis viverrini.
1/2016	Antibody Signatures Reflect Different Disease Pathologies in Patients With Schistosomiasis Due to Schistosoma japonicum.
11/2015	The Intestinal Microbiota Contributes to the Ability of Helminths to Modulate Allergic Inflammation.
8/2015	Diterpenoid alkaloids of Aconitum laciniatum and mitigation of inflammation by 14-O-acetylneoline in a murine model of ulcerative colitis.
10/2012	The tumorigenic liver fluke Opisthorchis viverrini--multiple pathways to cancer.
3/2011	Effect of hookworm infection on wheat challenge in celiac disease--a randomised double-blinded placebo controlled trial.

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Alex Loukas Research Topics

Disease

65	Infections 01/2022 - 01/2003
34	Hookworm Infections (Hookworm Infection) 01/2022 - 08/2004
26	Schistosomiasis (Bilharziasis) 11/2021 - 07/2006
24	Inflammation (Inflammations) 02/2024 - 08/2008
17	Neoplasms (Cancer) 09/2023 - 06/2007
15	Opisthorchiasis 01/2022 - 11/2008
14	Colitis 01/2022 - 04/2009
12	Reinfection 01/2022 - 07/2006
11	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 12/2022 - 03/2013
10	Cholangiocarcinoma 01/2020 - 01/2009
6	Persistent Infection 01/2022 - 03/2011
6	Wounds and Injuries (Trauma) 10/2018 - 02/2002
5	Fibrosis (Cirrhosis) 05/2021 - 10/2009
5	Parasitic Diseases (Parasitic Disease) 01/2021 - 01/2010
5	Celiac Disease (Celiac Sprue) 12/2020 - 03/2011
4	Necrosis 12/2022 - 11/2011
4	Schistosomiasis haematobia (Schistosomiasis haematobium) 01/2022 - 01/2020
3	Hypersensitivity (Allergy) 10/2022 - 03/2014
3	Body Weight (Weight, Body) 01/2022 - 01/2018
3	Asthma (Bronchial Asthma) 01/2022 - 01/2006
3	Malaria 01/2022 - 09/2003
3	Bile Duct Neoplasms (Bile Duct Cancer) 01/2021 - 01/2012
3	Neglected Diseases 04/2020 - 01/2011
3	Carcinogenesis 01/2018 - 06/2007
3	Echinococcosis (Hydatid Cysts) 08/2011 - 01/2006
2	Rheumatoid Arthritis 04/2022 - 01/2019
2	Experimental Arthritis 04/2022 - 01/2019
2	Arthritis (Polyarthritis) 04/2022 - 01/2019
2	Urinary Bladder Neoplasms (Bladder Cancer) 01/2022 - 01/2020
2	Nematode Infections 12/2021 - 01/2020
2	Infertility (Sterility) 09/2021 - 08/2011
2	Bites and Stings (Sting) 01/2021 - 01/2012
2	Weight Loss (Weight Reduction) 01/2021 - 08/2015
2	Communicable Diseases (Infectious Diseases) 11/2018 - 02/2015
2	Digestive System Diseases 01/2018 - 01/2017
2	Cutaneous Leishmaniasis 01/2012 - 11/2011
2	Cysts 08/2011 - 03/2008
2	Helminthiasis (Helminthiases) 11/2010 - 01/2006

Drug/Important Bio-Agent (IBA)

55	Proteins (Proteins, Gene)FDA Link 02/2024 - 02/2004
49	VaccinesIBA 01/2022 - 01/2003
23	AntigensIBA 01/2022 - 02/2005
12	CytokinesIBA 09/2023 - 11/2011
12	AntibodiesIBA 11/2021 - 10/2005
11	TetraspaninsIBA 01/2022 - 07/2006
8	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 03/2023 - 10/2009
8	Subunit VaccinesIBA 01/2022 - 01/2012
8	Biomarkers (Surrogate Marker)IBA 01/2022 - 01/2012
8	GranulinsIBA 01/2022 - 10/2011
8	ProteomeIBA 01/2021 - 01/2016
7	AnthelminticsIBA 12/2021 - 05/2006
7	Praziquantel (Biltricide)FDA Link 05/2021 - 01/2008
7	Glutens (Glutelin)IBA 12/2020 - 01/2011
7	EnzymesIBA 04/2020 - 08/2008
6	CarcinogensIBA 01/2022 - 06/2007
6	Peptides (Polypeptides)IBA 01/2022 - 01/2012
6	Peptide Hydrolases (Proteases)FDA Link 06/2013 - 09/2003
5	Immunoglobulin G (IgG)IBA 01/2022 - 11/2008
5	Immunoglobulin E (IgE)IBA 03/2014 - 02/2004
4	AllergensIBA 10/2022 - 01/2006
4	VenomsIBA 01/2021 - 02/2002
3	MicroRNAs (MicroRNA)IBA 05/2023 - 01/2018
3	Glucose (Dextrose)FDA LinkGeneric 01/2023 - 01/2020
3	InterleukinsIBA 12/2022 - 01/2012
3	InflammasomesIBA 11/2019 - 01/2018
3	Recombinant ProteinsIBA 10/2017 - 07/2006
3	Mebendazole (Anti-Worm)FDA Link 01/2016 - 05/2006
3	Interleukin-6 (Interleukin 6)IBA 11/2015 - 10/2009
3	Synthetic Vaccines (Recombinant Vaccines)IBA 03/2009 - 10/2005
2	ProgranulinsIBA 03/2023 - 01/2020
2	Blood Glucose (Blood Sugar)IBA 01/2023 - 01/2020
2	Protein Subunit VaccinesIBA 01/2022 - 09/2021
2	NitrosaminesIBA 01/2022 - 05/2011
2	EpitopesIBA 01/2022 - 01/2014
2	Albendazole (Albenza)FDA Link 12/2021 - 05/2006
2	Monoclonal AntibodiesIBA 07/2021 - 01/2015
2	Complex MixturesIBA 01/2021 - 03/2010
2	Sulfonic AcidsIBA 01/2021 - 04/2009
2	Interleukin-4 (Interleukin 4)IBA 01/2020 - 06/2013
2	Membrane Proteins (Integral Membrane Proteins)IBA 01/2019 - 03/2007
2	PhytochemicalsIBA 11/2018 - 08/2015
2	RNA (Ribonucleic Acid)IBA 01/2018 - 03/2014
2	Messenger RNA (mRNA)IBA 10/2017 - 04/2009
2	Hemoglobins (Hemoglobin)IBA 01/2015 - 03/2011
2	Formaldehyde (Formol)FDA Link 01/2015 - 03/2012
2	ImmunosorbentsIBA 01/2015 - 03/2012
2	ethyl acetateIBA 01/2015 - 03/2012
2	Interleukin-22 (IL-22)IBA 03/2013 - 02/2012
2	PeroxiredoxinsIBA 10/2012 - 03/2012
2	Cathepsin BIBA 03/2012 - 08/2011
2	Reactive Oxygen Species (Oxygen Radicals)IBA 03/2012 - 08/2008
2	AnnexinsIBA 08/2011 - 03/2010
2	SaposinsIBA 01/2011 - 11/2008
2	Interleukin-10 (Interleukin 10)IBA 01/2011 - 01/2006

Therapy/Procedure

14	Therapeutics 04/2022 - 01/2008
6	Mass Drug Administration 12/2017 - 06/2008
4	Drug Therapy (Chemotherapy) 03/2014 - 01/2008
3	Immunomodulation 12/2019 - 01/2017
2	Traditional Medicine (Folk Remedies) 02/2024 - 08/2015
2	Therapy with Helminths 01/2021 - 01/2019
2	Aftercare (After-Treatment) 01/2017 - 01/2012